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Melatonin has actually been revealed to possess anti-inflammatory effects, among a number of actions. Melatonin lowers tissue damage during inflammatory responses by a variety of means. Therefore melatonin, through its capability to directly scavenge hazardous free radicals, decreases macromolecular damage in all body organs. The free radicals and reactive oxygen as well as nitrogen varieties recognized to be scavenged by melatonin include the very hazardous hydroxyl radical, peroxynitrite anion, and also hypochlorous acid, to name a few. These agents all contribute to the inflammatory action and also connected cells destruction. In addition, melatonin has other means to decrease the damage arising from inflammation.
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