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Melatonin has been revealed to have anti-inflammatory effects, among a variety of activities. Melatonin reduces tissue damage during inflammatory responses by a number of methods. Thus melatonin, through its ability to directly scavenge hazardous totally free radicals, minimizes macromolecular damage in all body organs. The totally free radicals and also reactive oxygen and also nitrogen varieties recognized to be fed on by melatonin include the extremely harmful hydroxyl radical, peroxynitrite anion, as well as hypochlorous acid, among others. These representatives all add to the inflammatory action and associated cells devastation. In addition, melatonin has various other methods to lower the damage arising from inflammation.
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